Hope for vaccine: Novel coronavirus strains present little variability, research finds

New Delhi, August 4

In some “good news” for scientists engaged on a viable vaccine for COVID-19, a modern research has discovered that the SARS-CoV-2 virus behind the illness exhibits little variability, regardless of having at the least six strains.

Published within the journal Frontiers in Microbiology, the “most extensive” research ever carried out on SARS-CoV-2 sequencing drew from the evaluation of 48,635 coronavirus genomes, which had been remoted by researchers in labs all around the world.

The researchers on the University of Bologna in Italy mapped the unfold and the mutations of the virus throughout its journey to all continents.

The findings present that the novel coronavirus presents little variability, roughly seven mutations per pattern.

Common influenza has a variability fee that’s greater than double, the researchers stated.

“The SARS-CoV-2 coronavirus is presumably already optimised to affect human beings, and this explains its low evolutionary change,” stated Federico Giorgi, a researcher at University of Bologna, and coordinator of the research.

“This means that the treatments we are developing, including a vaccine, might be effective against all the virus strains,” Giorgi stated.

The researchers famous that at the moment there are six strains of the novel coronavirus.

The unique one is the L pressure, that appeared in Wuhan in December 2019. Its first mutation — the S pressure — appeared firstly of 2020, whereas, since mid-January, now we have had strains V and G, they stated.

To date pressure G is probably the most widespread: it mutated into strains GR and GH on the finish of February, in accordance with the researchers.

“Strain G and its related strains GR and GH are by far the most widespread, representing 74 per cent of all gene sequences we analysed,” stated Giorgi.

“They present four mutations, two of which are able to change the sequence of the RNA polymerase and Spike proteins of the virus. This characteristic probably facilitates the spread of the virus,” he stated.

Besides the six principal coronavirus strains, researchers recognized some rare mutations that, they stated, aren’t worrying in the intervening time however needs to be monitored. PTI


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